Indocyanine green (ICG) is a cyanine dye used in medical diagnostics. It is used for determining cardiac output, hepatic function, and liver blood flow, and for ophthalmic angiography. It has a peak spectral absorption close to 800 nm. These infrared frequencies penetrate retinal layers, allowing ICG angiography to image deeper patterns of circulation than fluorescein angiography. Conventional activated ICG dye, ICG-Sulfo-OSu, has been used for preparing ICG-antibody conjugates utilized in in vivo imaging research as antibody conjugates. However, the ICG hydrophobicity often causes some unspecific bindings. The PEG-modified ICG dyes are used to increase the hydrophobicity of the ICG dyes. The PEGylated ICGs shows better water solubility and significantly reducing unspecific binding.
Details
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Product Name
ICG-Sulfo-EG4-OSu
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Catalog No
Z0964
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ABT-Webpage
assaybiotechnology.com/ICG-Sulfo-EG4-OSu
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H-Phrases
H303, H313, H333
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Molecular weight
1177.36
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Product Legend
Chemical structure for ICG-Sulfo-EG4-OSu
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R-Phrase
R20, R21, R22
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Shipping
RT
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Solvent
DMSO
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Spectral Properties
Excitation (nm):789, Emission (nm):814, Correction factor (280 nm):0.076
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Storage
f/l
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Symbol
Xn
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UNSPEC Code
12171501
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