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D-Luciferin, Free Acid *Ultrapure Grade*

Catalog No : Z0278
  • Size
    25 mg
  • Price
    $75.00
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Luciferin is the most popular and versatile bioluminescent substrate. The firefly luciferase/luciferin bioluminescent system is found in the firefly (Photinus pyralis) and several other beetles. Luciferase oxidizes ATP-activated luciferin through a dioxetanone intermediate. Firefly luciferase produces light by the ATP-dependent oxidation of luciferin. The 560 nm chemiluminescence from this reaction peaks within seconds, with light output that is proportional to luciferase activity when luciferin and ATP are present in excess. Firefly luciferase has long been conjugated to antibodies and used as a label in immunoassays using luciferin as the substrate for detection. Compared to HRP and alkaline phosphatase, luciferase is less tolerant to chemical modifications. One particular advantage to the enzyme is that there is low endogenous luciferase activity in mammalian tissues besides its high sensitivity. Another important use of luciferase is in the area of hygiene monitoring. The luciferase/luciferin system can be used to detect contamination because ATP, present in all living organisms, is required to produce luminescence. The main application for this type of ATP bioluminescence is quality assurance by testing surfaces
Details
  • Product Name
  • Catalog No
  • Data Link
    12501
  • H-Phrases (GHS) for Dangerous Goods by EU 1272/2008
    H303, H313, H333
  • MSDS
    M12501
  • Shelf Life
    12 Months
  • Storage
    F/D/L
  • R-Phrase for Dangerous Goods
    R20, R21, R22
  • Symbol for Dangerous Compound by EU 67/548 EWG
    Xn
Application Images
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