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Anti-BOB.1 antibody [ABT-BOB1]

Catalog No : V0009
  • Applications
    IHC
  • Host Species
    Mouse
  • Reactivity
    Human
  • Size
    50ul
  • Price
    $175.00
BOB.1 or the B-cell-specific coactivator OBF-1; BOB1; OCA-B; OBF1 is the coactivator specific for B-cells and primarily restricted to matured B cells. This can be used successfully to analyze the development of B-cell at different stages as it has B-cell-specific, constitutive pattern of expression. In nodular lymphocyte with predominant Hodgkin lymphoma, the LP cells are routinely immunoreactive for BOB.1, while only a few cases of classical Hodgkin lymphoma demonstrate immunoreactivity to BOB.1. Immunoreactivity of weak to moderate extent can be observed in case of mantle cell lymphoma and marginal zone lymphoma.
Details
  • Product Name
    Anti-BOB.1 antibody [ABT-BOB1]
  • Catalog No
    V0009
  • Description
    Mouse monoclonal [ABT-BOB1] antibody to BOB1
  • Applications
    IHC
  • Clonality
    Monoclonal
  • Host Species
    Mouse
  • Reactivity
    Human
  • ABT Clone ID
    ABT-BOB1
  • Antigen Retrieval
    Heat-induced epitope retrieval (HIER)
  • Cell Marque/Ventana Control
    B-cell lymphoma, tonsil
  • Concentration
    0.6mg/ml
  • Dilution
    1:50-200
  • Entrez Gene ID (NCBI)
    5450
  • IHC Recommended control
    Normal Tonsil
  • IHC Target Name
    BOB.1
  • Immunogen
    Synthetic peptide
  • Localization
    Nuclear, Cytoplasmic
  • OMIM
    601206
  • Purification
    Immunogen affinity purified
  • Research
    B-cell lymphomas: Follicular, CLL/SLL, Mantle cell, Marginal zone bcl, lymphoplasmacytic, diffuse large cell lymphoma, Hodgkin Lymphoma: nodular lymphocyte predominant, T-cell rich LBCL, Acute myeloid leukemia: promyelocytic M3, megakaryoblastic M7
  • Retrieval buffer
    Citrate buffer of pH6.0
  • Source/Ig Isotype
    Mouse IgG
  • Storage/Stablility
    -20°C/1 year
  • Synonyms
    B-cell-specific coactivator OBF-1, BOB1, OCA-B, OBF1
  • UniProt Gene Name
    POU2AF1
  • UniProtKB
    Q16633
  • Volume
    2ml
Application Images
Image 1 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Classical Hodgkin lymphoma using BOB.1 antibody.
Image 2 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Hodgkin lymphoma using BOB.1 antibody.
Image 3 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Hodgkin lymphoma using BOB.1 antibody.
Image 4 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Hodgkin lymphoma using BOB.1 antibody.
Image 5 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Hodgkin lymphoma using BOB.1 antibody.
Image 6 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Tonsil using BOB.1 antibody.
Image 7 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Tonsil using BOB.1 antibody.
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