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Anti-Actin, smooth muscle (SMA) antibody [ABT-SMA]

Catalog No : V0004
  • Applications
    IHC
  • Host Species
    Mouse
  • Reactivity
    Human
  • Size
    100ul
  • Price
    $275.00
Actin for smooth muscles is a type of cytoskeletal proteins commonly expressed in eukaryotes. They mainly help in regulation of different functions of cells including contraction of muscle tissues, synthesis of mRNA, apoptosis etc. This product is the actin isoform, which is predominantly found in the cardiac tissues of the adults. Any modifications in this isoform have already been related to congenital heart diseases and hypertrophic cardiomyopathy. Monoclonal Anti-Actin, is a cardiac antibody with specificity for the cardiac α actin of human. It is also known as Alpha-actin-2, Cell growth-inhibiting gene 46 protein/Alpha-actin-3, or Gamma-2-actin.
Details
  • Product Name
    Anti-Actin, smooth muscle (SMA) antibody [ABT-SMA]
  • Catalog No
    V0004
  • Description
    Mouse monoclonal [ABT-MSA] antibody to SMA
  • Applications
    IHC
  • Clonality
    Monoclonal
  • Host Species
    Mouse
  • Reactivity
    Human
  • ABT Clone ID
    ABT-SMA
  • Antigen Retrieval
    Heat-induced epitope retrieval (HIER)
  • Cell Marque/Ventana Control
    Appendix
  • Dilution
    1:50-200
  • Entrez Gene ID (NCBI)
    59/72
  • IHC Recommended control
    Colon, Appendix, Uterus
  • IHC Target Name
    Actin, smooth muscle (SMA)
  • Immunogen
    Synthetic peptide
  • Localization
    Cytoplasmic
  • OMIM
    102620/102545
  • Purification
    Immunogen affinity purified
  • Research
    Muscle Malignant Tumors: leiomyosarcoma, rhabdomyosarcoma, Soft Tissue Neoplasms: Leiomyosarcoma, PEComa, alveolar soft part sarcoma, Spindle Cell Tumors: myofibroblastic tumor, endometrial stromal tumor, smooth muscle, fibromatosis, leiomyosarcoma
  • Retrieval buffer
    TRIS-EDTA of pH8.0
  • Source/Ig Isotype
    Mouse IgG
  • Storage/Stablility
    -20°C/1 year
  • Synonyms
    Alpha-actin-2, Cell growth-inhibiting gene 46 protein/Alpha-actin-3, Gamma-2-actin, Smooth muscle gamma-actin
  • UniProt Gene Name
    ACTA2/ACTG2
  • UniProtKB
    P62736/P63267
Application Images
Image 1 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Cardiac muscle using Actin, smooth muscle (SMA) antibody.
Image 2 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Cardiac muscle using Actin, smooth muscle (SMA) antibody.
Image 3 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Cardiac muscle using Actin, smooth muscle (SMA) antibody.
Image 4 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Colon using Actin, smooth muscle (SMA) antibody.
Image 5 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Colon using Actin, smooth muscle (SMA) antibody.
Image 6 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Colon using Actin, smooth muscle (SMA) antibody.
Image 7 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Leiomyoma using Actin, smooth muscle (SMA) antibody.
Image 8 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Skeletal muscle using Actin, smooth muscle (SMA) antibody.
Image 9 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Skeletal muscle using Actin, smooth muscle (SMA) antibody.
Image 10 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Skeletal muscle using Actin, smooth muscle (SMA) antibody.
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