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Anti-CA-125 antibody [ABT-MUC16]

Catalog No : V0010
  • Applications
    IHC
  • Host Species
    Mouse
  • Reactivity
    Human
  • Size
    50ul
  • Price
    $195.00
CA-125, also called Ovarian carcinoma antigen CA125; Ovarian cancer-related tumor marker CA125, is a monoclonal antibody that reacts with epithelioid mesothelioma, clear cell adenocarcinoma of the bladder, ovarian epithelioid malignancies, cervical papillary serous carcinoma, and endometrium adenocarcinoma. The antigen is resistant to formalin treatment allowing it to detect potential ovarian cancer with the help of immunohistochemistry. Usually, ovarian cancer is monitored using the serum assay of the protein. The antibody of CA-125 also interacts with seminal vesicle carcinoma antigens. The antigen is retreived by the Heat-induced epitope retrieval (HIER) system using the TRIS-EDTA buffer of pH - 8.0.
Details
  • Product Name
    Anti-CA-125 antibody [ABT-MUC16]
  • Catalog No
    V0010
  • Description
    Mouse monoclonal [ABT-MUC16] antibody to MUC16
  • Applications
    IHC
  • Clonality
    Monoclonal
  • Host Species
    Mouse
  • Reactivity
    Human
  • ABT Clone ID
    ABT-MUC16
  • Antigen Retrieval
    Heat-induced epitope retrieval (HIER)
  • Cell Marque/Ventana Control
    Ovarian carcinoma
  • Concentration
    0.9mg/ml
  • Dilution
    1:50-200
  • Entrez Gene ID (NCBI)
    94025
  • IHC Recommended control
    Ovarian serous carcinoma
  • IHC Target Name
    CA-125
  • Immunogen
    Synthetic peptide
  • Localization
    Membranous, Cytoplasmic
  • OMIM
    606154
  • Purification
    Immunogen affinity purified
  • Research
    Serous ovarian carcinoma, ovarian endometroid Carcinoma
  • Retrieval buffer
    TRIS-EDTA of pH8.0
  • Source/Ig Isotype
    Mouse IgG
  • Storage/Stablility
    -20°C/1 year
  • Synonyms
    Ovarian carcinoma antigen CA125, Ovarian cancer-related tumor marker CA125, CA-125
  • UniProt Gene Name
    MUC16
  • UniProtKB
    Q8WXI7
  • Volume
    2ml
Application Images
Image 1 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Mesothelioma using CA 125 (MUC16) antibody.
Image 2 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Mesothelioma using CA 125 (MUC16) antibody.
Image 3 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Ovarian serous carcinoma using CA 125 (MUC16) antibody.
Image 4 Immunohistochemistry analysis of Formalin-fixed, paraffin-embedded Human Ovarian serous carcinoma using CA 125 (MUC16) antibody.
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