Anti-Actin, sarcomeric muscle antibody [ABT-SCA]

For the process of attaching edges to nodes, it is straightforward to compute the likelihood using (2). However, because of the nature of weighted sampling without replacement, we have to, for each i, calculate the probability conditi onal on each of the Xi!Xi! permutations of the selected nodes and then aver age over all Xi!Xi! probabilities to arrive at the likelihood. As calculating the exact likelihood in this way is not computationally feasible because the factorial grows faster than the exponential function, we approximate the likelihood based on one permutation of weighted sampling without replacement instead. The contribution by the new edges brought by node i is